5-HT1D and 5-HT1E/1F binding sites in depressed suicides: increased 5-HT1D binding in globus pallidus but not cortex
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چکیده
منابع مشابه
5'-Phosphate-Binding Sites in Proteins
many enzymic reactions. Almost all these pyridoxal phosphate-dependent enzymes have an absorption band around 415nm, although most of them have higher peaks at 335 nm. The studies made with simple models have shown that the 415nm band is due to a Schiffbase in a hydrophilic medium [structure (I) of Scheme 1] (Matsushima & Martell, 1967). The 335nm band can be assigned either to the structure (I...
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The pharmacological characteristics of hindlimb scratching induced by serotonergic compounds were studied. We conclude that hindlimb scratching induced by serotonergic compounds is mediated by a serotonin1D (5-HT1D) or 5-HT1D-like receptor outside the blood-brain barrier because hindlimb scratching could be induced by s.c. injection of 5-methoxytryptamine (5-MeOT), 5-carboxamidotryptamine (5-CT...
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Endogenous [5-methionine]enkephalin (Metenkephalin) and [5-leucine]enkephalin (Leu-enkephalin) are released from perfused slices of rat globus pallidus by increased K(+) in a Ca(2+)-dependent manner. Tissue perfused for 40 min contained only 26% of the Met-enkephalin and 44% of the Leu-enkephalin found in the freshly dissected tissue. After perfusion, the mean (+/-SEM) ratio (wt/wt) of Met-enke...
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Pancreatic ductal adenocarcinoma is characterized by extensive local tumor invasion, metastasis and early systemic dissemination. The vast majority of pancreatic cancer (PaCa) patients already have metastatic complications at the time of diagnosis, and the death rate of this lethal type of cancer has increased over the past decades. Thus, efforts at identifying novel molecularly targeted therap...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 1997
ISSN: 1359-4184,1476-5578
DOI: 10.1038/sj.mp.4000259